Life on Earth depends on the ability of cells to duplicate their genetic material, encoded in DNA molecules, and pass this information on to the next generation. Elucidation of the molecular mechanism ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

DURHAM, N.C. -- Biochemists have performed detailed structural studies that reveal for the first time how an enzyme key to DNA replication stalls when an error occurs ...