The Cucurbitaceae family, comprising economically important crops such as cucumber, melon, and watermelon, exhibits remarkable phenotypic diversity in traits including fruit size, shape, and flesh ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer. DNA is well-known for its double helix shape. But the human genome ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D.

A major cardiovascular risk factor is thickening of the heart walls (hypertrophy), which can result from high blood pressure—but is also linked to inherited diseases of the heart which can lead to ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell nuclei are condensed in flowering plants has been a mystery, until now. Researchers have long sought an efficient way to ...

WTOP’s Matt Kaufax takes an even deeper dive into the Smithsonian Natural History Museum’s “Ocean Library” through DNA collection.