UC Santa Cruz has a long history of pioneering advances in genomics research. The first working draft of a human genome sequence was assembled on our campus in 2000, which has led to enormous leaps in ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Our records of the human genome may still be missing tens of thousands of 'dark' genes. These hard-to-detect sequences of genetic material can code for tiny proteins, some involved in disease ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published in Nature Communications. Researchers ...