The contribution of different nicotinic acetylcholine (ACh) receptor (nAChR) oligomers to nicotine addiction is being explored in mice, using novel strategies including deletion of nAChR subunit genes ...

Introduction: Cigarette smoking continues to be one of the most important behavioral causes of morbidity and mortality in the world. Varenicline, an α4β2 nicotinic acetylcholine receptor (nAChR) ...

This is a preview. Log in through your library . Abstract Emerging studies indicate that striatal cholinergic interneurons play an important role in synaptic plasticity and motor control under normal ...

Nicotine protects the brain against the loss of dopamine neurons, a characteristic sign of Parkinson’s disease, according to a study published this week in The FASEB Journal. By activating the alpha-7 ...

A modified version of nicotine, the addictive ingredient in cigarettes, appeared in the U.S. vaping market in May 2023, prompting alarm among tobacco researchers. These products are being marketed as ...

SEATTLE and VANCOUVER, British Columbia, Oct. 17, 2025 (GLOBE NEWSWIRE) -- Achieve Life Sciences, Inc. (Nasdaq: ACHV), a late-stage specialty pharmaceutical company focused on the global development ...

When we hear the word “nicotine,” most of us think about vaping, cigarettes, addiction, and lung cancer. But beneath this stigma lies an interesting paradox: nicotine, the same compound that makes ...

Drug improves memory in patients with mild cognitive impairment, study finds. Jan. 9, 2012— -- The nicotine patch designed to help people quit smoking can also improve memory in older adults with ...