In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...
Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development of therapeutic ...
Reviewed by Michael Greenwood, M.Sc. In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug ...
Chemists are taking a p[h]age from bacteria's playbook in order to beat viruses at their own game and develop new drugs to fight cancer and a host of other human diseases in the process. Chemists at ...
Recent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gaps and limitations associated with next generation sequencing ...
Phage display is an increasingly popular, robust, and rapid method of antibody identification, particularly for antigens not amenable to antibody discovery using traditional hybridoma technology.
Company will combine this technology with ribosome display to increase speed and reliability of screening. Scil Proteins acquired a phage-display technology known as Tat Phage display from the German ...
Researchers have developed a simple, fast, and standardized method for measuring phage virulence quantitatively, which can expediate phage therapy development by allowing robust individual and ...
mRNA display is a technique that can identify proteins which bind to specific regions in DNA. This method has several advantages over other methods, such as yeast-to-hybrid, immunoprecipitation, phage ...