A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole (receptor) formed by a protein's three-dimensional structure and a molecule ...

Protein arginylation is an evolutionarily conserved post‐translational modification whereby arginine is covalently attached to specific residues on target proteins. Mediated principally by the enzyme ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall. McMaster ...

The Abu-Remaileh Lab published an atlas of proteins, found in lysosomes across different brain cell types, to advance research on neurodegenerative diseases.

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

A surprising new function of essential hearing proteins may explain why some genetic mutations and common antibiotics lead to permanent deafness.

Claudia Rückert, Ph.D., is an assistant professor in the Department of Biochemistry & Molecular Biology at the University of Nevada, Reno. She received her bachelor’s degree in biology and master's ...

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don ...

A new study has identified specific cellular machinery that helps brain cells dispose of toxic proteins associated with Alzheimer’s disease. By screening thousands of genes in lab-grown human neurons, ...