Lambda's 'genetic switch' responds in a dramatic all-or-none fashion to an environmental signal, activating transcription of certain genes as it turns off others. The switch illustrates principal ...

Macrophages have a central role in innate immunity, but they also play a part in the coordination of metabolic inflammation linked to metabolic diseases, including obesity and T2D 1,2. As obesity ...

A high throughput screen of >30,000 diverse repressor domains from across the tree of life identifies repressor domains with unique structures that underpin enhanced epigenetic effector domain potency ...