Figure 1: SPD-1 PRC1 and ZEN-4 MKLP1 are required for central spindle stabilization and bundling. Figure 2: A subset of kinetochore proteins are involved in central spindle assembly. Figure 3: The BUB ...

近日，四川大学林宏辉/邓星光团队在Science Advances发表了题为Arabidopsis KNL1 Recruits Type One Protein Phosphatase to Kinetochores to Silence the ...

Mitotic exit follows shortly after microtubule attachment of the last unattached kinetochore. Two new studies illustrate the molecular basis of this dependency. At metaphase, all sister chromatid ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...