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Structure:揭示IL-12信号起始的分子机制
白细胞介素-12(IL-12)家族的细胞因子由α亚基(p35、p19和p28)和β亚基(p40和EBI3)构成,具有形成异源二聚体、亚基和信号组分共享的特性。目前在人体内确定的家族成员包括IL-12(由p35和p40亚基结合形成)、IL-23(由p19和p40亚基结合形成)、IL-27(由p28和EBI3亚 ...
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