I have been lucky to review a lot of Lexus vehicles over the years, but the LC 500 has always occupied a special place in the ...

Novo Nordisk is paying $240 million for global rights to a Phase 3-ready drug from Omeros that could rival immune disorder medications currently available from companies such as AstraZeneca, Novartis, ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

Scientists at the University of Pennsylvania have uncovered the mathematical rules that govern one of the body’s oldest and most important immune system defenses, the complement system, according to ...

Complement C3 ELISA Kits are specialized diagnostic tools used to measure the level of complement component C3 in serum, plasma, or other biological samples. C3 is a crucial protein in the complement ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system plays crucial roles in ...

Researchers identify a new player in human immunity that can go rogue and turn the immune system against the body’s own tissues. The protein, called granzyme K, whose role until now was unclear, ...