Abstract: Multiple Sequence Alignment (MSA) is a fundamental NP-hard problem in Bioinformatics, central to numerous sequence analysis tasks. Despite extensive research, existing approaches still ...

Global data demand continues to grow at an exponential rate, driven by emerging applications in cloud computing, artificial intelligence, autonomous systems, and high-bandwidth communications. Even ...

In this tutorial, we demonstrate how to build an advanced yet accessible Bioinformatics AI Agent using Biopython and popular Python libraries, designed to run seamlessly in Google Colab. By combining ...

i-Motifs (iMs) are cytosine-rich, four-stranded DNA structures with emerging roles in gene regulation and genome stability. Despite their biological relevance, genome-wide prediction of iM-forming ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...

This study introduces MMPred, a software tool integrating epitope prediction and sequence alignment algorithms to simplify the setup of computational analyses aimed at the generation, investigation or ...

I may be misunderstanding, but is there a way to convert long sequences like chromosomes from hal to fasta or phylip multiple alignment formats? I've tried cactus-hal2maf and then various maf 2 fasta ...

Current methods of assessing the similarity between proteins are based on protein sequence alignment. However, alignment is ineffective for intrinsically disordered regions (IDRs) given their rapid ...