Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

We wish to thank the entire Kuzminov lab for their support and encouragement with this project. This work was supported by the grants ## GM 073115 and GM 132484 from the NIH.

Scientific progress depends on results that can be repeated – yet across disciplines, too many experiments fail that test. From medicine to economics, the replication crisis reveals not just flawed ...

DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates (dNTPs)—dATP, dTTP, dGTP, and dCTP. Cells constantly need these molecules ...

Science is a process of continuous discovery, built on the foundation of prior research. A core principle of the scientific method is that experiments should be reproducible, meaning other scientists ...

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Cory Benfield discusses the evolution of ...

Amanda Kay Montoya is an Associate Professor at the University of California, Los Angeles. She serves on the Board of Directors for the Center for Open Science. She receives funding from the ...

Kafka replication is a critical mechanism for ensuring data reliability, fault tolerance, and high availability in distributed streaming systems. This comprehensive blog examines the fundamental ...

DNA replication is one of the most well-orchestrated cellular processes that needs to proceed in a faithful and timely manner. However, this process is continuously challenged, leading to stalled ...

DNA replication is fundamental to life, yet the processes employed by archaea defy simple classification. Historically, scientists grouped archaea with bacteria due to their prokaryotic structure, but ...

I read with interest your article on the White House’s response to the replication crisis in biomedical science. You cite the Center for Open Science’s project, which couldn’t replicate 54% of ...